Publications
Alva Innovations, we provide insightful research and analysis in technology and innovation. Explore our publications to stay informed on our latest contributions and industry developments.
Phenolic Preservatives Are Not the Sole Cause of Eosinophilic Infiltration at Infusion Pump Sites
Our research highlights that skin reactions and discomfort from insulin infusion pumps can impact user adherence. We found eosinophils, a type of immune cell, present in the skin after using both insulin pumps and glucose sensors. This suggests that factors beyond the pumps may contribute to these skin issues.
Microglia Mediate Metabolic Dysfunction From Common Air Pollutants Through NF-κB Signaling
Our research highlights the significant health challenge posed by type 2 diabetes (T2D) and how immune responses in the brain may contribute to its onset. We found that targeting specific pathways in immune cells helped reduce harmful brain changes caused by benzene exposure and improved overall energy balance in mice. This suggests potential new ways to protect against diabetes linked to environmental toxins.
Insulin Derived Fibrils Induce Cytotoxicity in vitro and Trigger Inflammation in Murine Models
This study explores how insulin delivery can affect people with diabetes. We found that insulin can form harmful structures that may cause inflammation and damage to the skin at injection sites. Understanding effects can help improve diabetes management and minimize complications.